宫颈阴道分泌物中的胎儿纤连蛋白预测早产  

FETAL FIBRONECTIN IN CERVICOVAGINAL SECRETIONS FOR PREDICTION OF PRETERM LABOR

作　　者：李小毛[1] 张新玲[1] 郑荣琴[1] 杨越波[1] 侯红瑛[1] 

机构地区：[1]广州市中山大学附属第三医院妇产科,510630

出　　处：《中国现代医学杂志》2003年第7期58-59,61,共3页China Journal of Modern Medicine

基　　金：广东省科委科研基金 (1998-0 4)资助课题

摘　　要：目的 :探讨宫颈阴道分泌物中胎儿纤连蛋白 (FFN)与早产的关系。方法 :选择先兆早产与同期正常孕妇共 10 8例 ,应用酶联免疫法检测其宫颈阴道分泌物中胎儿纤连蛋白的含量 ,并追踪其妊娠结局。结果 :先兆早产组、正常妊娠组胎儿纤连蛋白的平均浓度分别为 82 .1± 3.7ng/ml和 2 3.4± 2 .6ng/ml;早产组 2 7例 ,足月产组 81例 ,胎儿纤连蛋白的平均浓度分别为 137.1± 3.0ng/ml和 2 4 .2± 2 .9ng/ml,两组结果差异有统计学意义 (P <0 .0 5 )。结论 :宫颈阴道分泌物中的胎儿纤连蛋白可作为早产预测的客观指标。Objective:To determine the value of fetal fibronectin (FFN) in cervicovaginal secretions in prediction of preterm labor(PTL).Methods:Fetal fibronectin in cervicovaginal secretions of 108 cases was measured by enzyme-linked immunosorbent assay (ELISA)methods. The outcomes of pregnancies were followed up.Results:The average concentrations of FFN in threatened PTL group and normal group were respectively 82.1±3.7 ng/ml and 23.4±2.6 ng/ml;in 27 cases with PTL and in 81 cases with term labor were respectively 137.1±3.0 ng/ml and 24.2±2.9 ng/ml. There were statistically significant differences between the two groups ( P <0.05).Conclusion:Fetal fibronectin in cervicovaginal secretions can be used as the objective indicator for prediction of preterm labor.

关 键 词：胎儿纤连蛋白 分娩 早产 宫颈阴道分泌物 

分 类 号：R714.56[医药卫生—妇产科学]