苍白秤钩风中脱皮甾酮类化学成分的研究(英文)  

ECDYSTEROIDS FROM THE STEMS OF DIPLOCLISIA GLAUCESCENS

作　　者：黄孝春[1] 郭跃伟[1] 周文亮[2] 左建平[2] 王峥涛[2] 

机构地区：[1]中国科学院上海生命科学院药物研究所新药研究国家重点实验室,上海200031 [2]上海中医药大学中药研究所,上海200032

出　　处：《天然产物研究与开发》2003年第2期93-97,共5页Natural Product Research and Development

基　　金：ThisresearchissupportedbyNationalScienceFoundationforOutstandingYouth(30125044)andthe"FoundationforScholarsComeBackfromAbroad"providedbyMinistryofEducation,MinistryofPersonnel,andChineseAcademyofSciences

摘　　要：从中国广西药用植物苍白秤钩风 (Diploclisiaglaucescens)藤茎的 95 %乙醇提取物中分离得到 5个脱皮甾酮类化合物 ( 1 5 )。通过NMR、MS以及化学沟通等方法分别将其结构鉴定为 paristeroneC 2 0 ,2 2 monoacetonide( 1) ,paristerone( 2 ) ,ecdysterone( 3) ,makisteroneC( 4 )和capisterone( 5 )。化合物 1为首次从自然界分得的天然产物 ,2 ,4 。Five ecdysteroids were isolated from the EtOH extract of the stems of Diploclisia glaucescens. Their structures were identified as paristerone 20,22 monoacetonide(1),paristerone(2),β ecdysterone(3),makisterone C(4)and capitasterone(5),respectively,on the basis of chemical and physical evidence.This is the first report of paristerone 20,22 monoacetonide isolated from natural source.Compounds 2,4,and 5 were also isolated for the first time from D.glaucescens .

关 键 词：苍白秤钩风 脱皮甾酮类 化学成分 结构鉴定 天然产物 药用植物 

分 类 号：Q949.746.9[生物学—植物学] R284.1[医药卫生—中药学]