门冬氨酸钾镁葡萄糖注射液中L-门冬氨酸的HPLC测定  

Determination of Aspartic Acid in Potassium Magnesium Aspartate and Glucose Injection by HPLC

作　　者：高春[1] 戴红[1] 姚瑛[1] 高恒莹[1] 

机构地区：[1]北京市药品检验所,北京100035

出　　处：《中国医药工业杂志》2003年第5期244-245,共2页Chinese Journal of Pharmaceuticals

摘　　要：建立了 HPL C法测定门冬氨酸钾镁葡萄糖注射液中 L-门冬氨酸的含量。采用 KR10 0 - 5 NH2 柱 ,乙腈 -0 .0 5 m ol/ L磷酸二氢钾缓冲液 (6 0∶ 4 0 )为流动相 ,检测波长为 2 14 nm。方法平均回收率为 10 0 .5 % ,RSD为0 .91%。A HPLC method for determination of aspartic acid in potassium magnesium aspartate and glucose injection was presented. A KR100 5NH 2 column was used, with mobile phase of acetonitrile 0.5mol/L potassium dihydrogen phosphate buffer solution (60∶40), at detection wavelength of 214nm. The average recovery was 100.5% with RSD of 0.91%.

关 键 词：门冬氨酸 高效液相色谱法 测定 

分 类 号：TQ460.72[医药卫生—药物分析学] O657.72[化学工程—制药化工]