提取苯乙酸工艺改进  

The Discussion of Pheny Acetic Acid Process

作　　者：孙旭明[1] 郭云波[1] 白向荣[1] 

机构地区：[1]哈药集团制药总厂,150086

出　　处：《黑龙江医药》2003年第3期213-214,共2页Heilongjiang Medicine journal

摘　　要：苯乙酸是青霉素工业钾盐生产的主要原料之一。在6—APA生产过程中,其中主要副产物为苯乙酸。它是在6—APA的萃取过程中存留于二氨甲烷相之中。本文主要目的是通过对提取苯乙酸工艺中控制条件:温度、PH值、时间的变化,进一步优化苯乙酸的提取工艺,使生产出的苯乙酸质量达到青霉素工业钾盐的原料标准。本工艺已经应用于工业生产中,且收到了明显效果。Pheny acetic acid(PAA)is the by—product in producing 6—APA,which also is one of the major stuff in producing Pencillin a Kalaum(PenG--K) salt,and it is abstracted from dichlormethane phase in producing 6—APA.Objective:Changing PAA process control condition, PH,temperture,time,in order to optimize PAA abstracting process,then the gained PAA can be achieved pencillin industrial salt stuff request.Result:it has been used in industrial producing and received apparent effect.

关 键 词：提取工艺 改进 苯乙酸 PH值 温度 

分 类 号：TQ460.6[化学工程—制药化工]