慢性阻塞性肺疾病急性加重期血液流变性观察  

Observation of Hemorheological Characteristics on Patients with COPD During Acute Exacerbation

作　　者：周强 张文 黄宪章 

机构地区：[1]广州中医药大学第二附属医院检验科,邮政编码广州510120

出　　处：《微循环学杂志》2003年第2期32-33,共2页Chinese Journal of Microcirculation

摘　　要：目的 :观察慢性阻塞性肺疾病 (COPD)急性加重期患者血液流变学特性。方法 :检测6 0例急性加重期、4 5例稳定期患者及 12 0例健康体检者的全血粘度、血浆粘度、血沉、红细胞压积和纤维蛋白原等血液流变学指标。结果 :COPD急性加重期患者与COPD稳定期患者和健康体检者血液流变测定值有显著性差异 (P <0 .0 5 ) ,除血浆粘度外其余项目测定值均有统计学意义 (P <0 .0 5 )。结论 :COPD急性加重期病人血液流变性有明显改变 ,可为病情评估。Objective: To observe the hemorheological characteristics of patients with chronic obstructive pulmonary disease(COPD) during acute exacerbation.Method: To measure the whole blood viscosity,plasma viscosity,erythrocyte sedimentation rate(ESR),hematocrcit(HCT),fibrinogen and other hemorheological indixes in 60 COPD patients during acute exacerbation,45 COPD patients during stable stage and 120 healthy people.Results: All hemorheological indixes except plasma viscosity were significant difference among three groups.Conclusion: The blood rheology characteristics of patients with COPD during acute exacerbation changed obviously.It may contribute to evaluement of diagnosis,treat and prognosis.

关 键 词：慢性阻塞性肺疾病 急性加重期 血液流变性 全血高切粘度 全血低切粘度 红细胞压积 

分 类 号：R563[医药卫生—呼吸系统] R331.1[医药卫生—内科学]