饮水矿化丸的卫生安全性评价  

Toxicological Safety Assessment on Artificial Mineral Water Pills

作　　者：冯利红[1] 李天源 马蔚[1] 王菲[1] 

机构地区：[1]天津市卫生防病中心环境卫生学分部,天津300011 [2]天津市起源新技术开发中心,天津300100

出　　处：《环境与健康杂志》2003年第3期161-163,共3页Journal of Environment and Health

摘　　要：目的矿化丸是通过将多种微量元素以特殊方法载入陶瓷载体而制成,经用纯净水浸泡后可使水质矿化。为判定其对人体健康是否产生危害,特进行了卫生安全性实验。方法采用急性经口毒性实验、小鼠微核实验、小鼠精子畸形实验、Ames实验进行毒理学研究,按《生活饮用水标准检验法》、《饮用天然矿泉水检验方法》进行微量元素、重金属含量及放射性物质含量的测定。结果经矿化丸矿化后的水中微量元素、重金属、放射性物质含量均符合GB8537-1995《饮用天然矿泉水》、GB5749-1985《生活饮用水卫生标准》的要求。矿化丸经口急性毒性属实际无毒级,致突变实验结果为阴性。结论正常饮用其矿化后的水,在卫生学上是安全的。Objective Artificial mineral water pills were made by loading many kinds of trace elements into the ceramic carrier.Pure water could be mineralized after dipping the pills into the water.To assess the possible hazardous effects on the human health induced by the pills,a series of hygienic and toxicological experiments on the pills were carried out.Methods Acute oral toxicity test,micronucleus test of mice bone marrow cells,sperm abnormality test in mice and Ames test were con-ducted.Contents of trace elements,heavy metals and radioactivity in the mineralized water were determined according to the examination methods in Standard Examination Methods for Drinking Water and Examination Methods for Drinking Natural Min-eral Water.Results The contents of trace elements,heavy metals and radioactivity in mineralized water met the requirements of GB5749-1985Sanitary Standard for Drinking Water and GB8537-1995Sanitary Standard for Drinking Natural Mineral Wa-ter.Mineral pills were classified as actually non-toxic and the results of micronucleus test of mice bone marrow cells,sperm ab-normality test in mice and Ames test were negative.Conclusion Mineralized drinking water treated by artificial mineral pills were safe.

关 键 词：饮水 急性毒性 微核 精子畸形 重金属 矿化丸 

分 类 号：R994.6[医药卫生—毒理学]