正交试验法研究复方补肾颗粒提取工艺  

The Extracting Technology for Compoun Bushen Granule by Orthogonal Test

作　　者：曹妹芳[1] 刘瑾[1] 

机构地区：[1]上海中医药大学附属曙光医院,上海200021

出　　处：《时珍国医国药》2003年第5期264-265,共2页Lishizhen Medicine and Materia Medica Research

摘　　要：目的 :优选复方补肾颗粒的最佳提取工艺。方法 :正交试验法 L 9( 3 4 ) ,以复方补肾方中的补骨脂素和总固物为考察指标 ,对影响复方补肾颗粒提取工艺的因素进行了研究。结果 :优选出复方补肾颗粒的制备工艺 ,重复试验结果满意。结论 :用 10倍量水 80℃煎煮 2次 ,90 min/次的方法制备的成品 ,质量稳定 。Objective: To optimize the extraction process of Compound Bushen Granule. Methods: The optimum extraction condition was studied by orthogonal test in psoralen content and extract yield as markers. Results: The optimum extraction process was reliable. Conclusion: The optimum extraction process were: 10 times of water, extracting 2 times in 90℃,90 min each time. The extract was stable in quality and psoralen content in the extract was high.

关 键 词：复方补肾颗粒 正交试验法 制备工艺 补骨脂素 

分 类 号：R284.2[医药卫生—中药学]