聚氯乙烯膜普鲁卡因选择电极的研制与应用  

Preparation and Application of PVC Membrane-Procaine Selective Electrode

作　　者：李东辉[1] 孙挺[2] 丁扬栋[1] 鄂义峰[1] 安丽茹 

机构地区：[1]锦州医学院化学教研室,辽宁锦州121001 [2]东北大学理学院,辽宁沈阳110004 [3]铁岭药品检验所,辽宁铁岭112000

出　　处：《分析测试学报》2003年第3期104-105,共2页Journal of Instrumental Analysis

摘　　要：研制了一种以普鲁卡因碘化物与碘化铋形成的缔合物为电活性物质的PVC(聚氯乙烯 )膜普鲁卡因选择电极 ,测定了普鲁卡因注射液的含量 ;电极的线性响应范围1.0×10 -1～6.3×10 -5mol/L,级差电位为45mV/pc ,检出限为3.4×10-5 mol/L ;该电极响应迅速 。A new polyvinyl chloride(PVC) membrane-procaine selective electrode was prepared based on formation of association molecule of procaine iodide with bismuth iodide in PVC membrane. The electrode showed Nernst response for procaine ranged from 1.0×10-1 to 6.3×10-5 mol/L with a slope of 45 mV/pc. The detection limit was 3.4×10-5 mol/L. The electrode has the advantages of fast response and good repeatability. It was used to determine procaine hydrochloride injection with results agreeing with those of Chinese pharmacopoeia method.

关 键 词：聚氯乙烯膜 普鲁卡因 离子选择电极 局部麻醉药 注射液 分析 

分 类 号：R971.2[医药卫生—药品] R917[医药卫生—药学]