Separation of Ephedrines Using 1-Butyl-3-methylimidazolium-tetrafluoroborate Ionic Liquids as Eluent in High-performance Liquid Chromatography (HPLC)  

作　　者：Li Jun HE, Wen Zhu ZHANG, Bo WEN, Xia LIU, Sheng Xiang JIANG* Lanzhou Institute of Chemical Physics, Chinese Academy of Science, Lanzhou 730000 

出　　处：《Chinese Chemical Letters》2003年第6期603-604,共2页中国化学快报（英文版）

摘　　要：A simple, effective HPLC method for separation of ephedrines was achieved by using 1-butyl-3-methylimidazolium-tetrafluoroborate ionic liquid solution (0.1% v/v) as eluent at pH 3.0. The involved mechanism may be due to that the imidazolium cations can effectively shield the silanol groups of alkylsilica surface, thereby decreasing band tailing and increasing the separation efficiency.A simple, effective HPLC method for separation of ephedrines was achieved by using 1-butyl-3-methylimidazolium-tetrafluoroborate ionic liquid solution (0.1% v/v) as eluent at pH 3.0. The involved mechanism may be due to that the imidazolium cations can effectively shield the silanol groups of alkylsilica surface, thereby decreasing band tailing and increasing the separation efficiency.

关 键 词：Ionic liquid EPHEDRINE HPLC. 

分 类 号：O629[理学—有机化学]