HPLC测定消斑丽肤霜中栀子苷的含量  

Determination of geniposide in Xiaobanlifu Unguentum by HPLC

作　　者：曾德成[1] 

机构地区：[1]四川光大制药有限公司,四川彭州611930

出　　处：《中成药》2003年第5期365-368,共4页Chinese Traditional Patent Medicine

摘　　要：目的 :建立消斑丽肤霜中栀子苷的含量测定方法。方法 :HPLC测定消斑丽肤霜中栀子苷的含量。采用InertsilC18柱 ,以流动相 :甲醇 0 .0 5mol·L-1磷酸二氢钾 醋酸 异丙醇 ( 6 7∶173∶4∶4) ;检测波长 :2 38nm。结果 :此方法线性关系良好(r =0 .9994) ,平均回收率为 97.3 % ,相对标准偏差RSD为 1.94% (n =5 )。结论 :方法较简单 ,准确 ,可用于消斑丽肤霜质量控制。Objective: To establish the determination method of geniposide in Xiaobanlifu Unguentum. Methods: HPLC was performed to determine the content of geniposide on Inertsil ODS-3 column, using methanol-potassium dihydrogen phosphate-acetic acid-isopropyl alcohol (67∶173∶4∶4,v/v) as a mobile phase and detection wavelength at 238nm. Results: The linearity of this method was good, and the averge recovery was 97.3%, RSD=1.94%. Conclusion: This method was relatively simple and accurate, and available for the quality control in Xiaobanlifu Unguentum.

关 键 词：消斑丽肤霜 桅子苷 HPLC 测定方法 

分 类 号：R927.2[医药卫生—药学]