合成(Z)-乙烯酮缩硒硫醇的新方法  

New Synthetic Method of (Z)-Ketene Selenothioacetales

作　　者：钟平[1] 

机构地区：[1]温州师范学院化学与材料科学学院 浙江 温州 325027

出　　处：《温州师范学院学报》2003年第2期1-4,共4页Journal of Wenzhou Teachers College(Philosophy and Social Science Edition)

基　　金：国家自然科学基金(20272043);浙江省自然科学基金(201015)

摘　　要：炔基硒基锂盐与Cp2Zr(H)Cl(Cp=n5-C5H5)在THF中反应得到中间产物α-锆取代的乙烯基硒基锂,接着与卤代烃反应得到α-锆取代的乙烯基烃基硒醚,进一步与烷基硫氯反应得到(Z)-乙烯酮缩硒硫醇.上述反应有很好的区域选择性和立体选择性.Lithium alkynylselenolate anions react completely with 1.0 equiv of Cp2Zr(H)Cl in THF at room temperature to give exclusively the α -zirconated vinylselenolate intermediates 3, which by treatment with an alkylsulfenyl chloride afforded the α -zirconated vinyl alkylselenides intermediates 4. Reaction of 4 with alkylsulfenyl chlorides results in the formation of (Z)-ketene selenothioacetals 5 with total control of the regio- and stereochemistry.

关 键 词：端炔 烷基硫氯 (Z)—乙烯酮缩硒硫醇 锆氢化反应 

分 类 号：O627.4[理学—有机化学]