自身抗体阴性的类风湿关节炎患者临床特征分析  

Analysis of the Clinical Characteristics of Autoantibody Negative Patients with Rheumatoid Arthritis

作　　者：郭静[1] 闫慧明[2] 孙秀丽[1] 

机构地区：[1]包头市中心医院肾内风湿免疫科,内蒙古包头014060 [2]包头医学院第二附属医院风湿科,内蒙古包头014030

出　　处：《内蒙古民族大学学报（自然科学版）》2015年第4期352-354,共3页Journal of Inner Mongolia Minzu University：Natural Sciences

摘　　要：目的:回顾性分析自身抗体阴性类风湿关节炎患者的实验室及临床特点.方法:随机入选RA患者160例,分析比较自身阴性RA患者的实验室及临床特点.结果:(1)自身抗体阴性组占9.4%,三组RA患者在性别构成、平均年龄方面比较均无统计学差异.(2)在压痛关节数方面,自身抗体阴性组与其他两组比较有明显统计学差异(P<0.05).(3)实验室指标比较,自身抗体阴性组的Ig M水平显著低于其他两组,具有统计学差异(P<0.05).结论:自身抗体阴性的类风湿关节炎患者并不少见,常出现在关节压痛数少、Ig M水平低的RA患者中.Objective: To analyse the laboratory and clinical features of autoantibody negative patients with rheumatoid arthritis(RA). Methods: The clinical and laboratory features parameters were compared between autoantibody negative and posive group in 160 randomly selected RA patients. Results: 1. The rates of autoantibody negative were 9.4%.The gender composition and average age of patients in three RA groups were no significantly differences. 2. The tender joint counts of patients in autoantibody negative group were less than other two groups(P< 0.05). 3. For laboratory indexes, the autoantibody negative RA patients showed lower levels on Ig M than other two groups(P< 0.05). Conclusion: The autoantibody negative RA patients are not uncommon, and are more likely appear in RA patients who have tender joint counts and lower Ig M levels.

关 键 词：类风湿关节炎 自身抗体 

分 类 号：R593.22[医药卫生—内科学]