水溶液中甘氨酰-缬氨酸与稀土配位作用及其配合物构象的NMR研究  

NMR Studies on the Coordination of Rare Earths with Glycyl-DL-Valine and the Conformation of their Complex in Aqueous Solution

作　　者：柳建学 任吉民[1] 牛春吉[1] 裴奉奎[1] 王文韵[1] 倪嘉缵[1] 

机构地区：[1]中国科学院长春应用化学研究所,长春130022

出　　处：《化学学报》1992年第2期175-179,共5页Acta Chimica Sinica

基　　金：国家自然科学基金

摘　　要：本文测定了在三种不同稀土离子(镧La^(3+)、钬Ho^(3+)和镱Yb^(3+)的水溶液中甘氨酰-缬氨酸的~1H和^(13)C稀土诱导位移。计算了Ho、Yb与甘氨酰-缬氨酸配合物的稳定常数,讨论了稀土与该配体的配位作用及对配合物构象进行研究,发现配位后的甘氨酰-缬氨酸以一种空间位阻较小的伸展构象存在。In this paper lanthanide-induced shifts have been measured for ^(13)C and ~1H nuclei of glycyl-DL-valine in the presence of three lanthanide cations (La^(3+), Ho^(3+) and Yb^(3+)) in aqueous solution. The stability constants of the coordination compounds of rare earths (Ho, Yb) with glycyl-DL-valine have been calculated. The coordination of rare earths with the ligand has been discussed. The simulation for conformation of lanthanide coordination compounds with glycyl-DL-valine shows that the ligand is coordinated to lanthanide ion through oxygen atoms of carboxyl group and the bond length of Ln—O is 0.226nm. In the coordination compounds glycyl-DL-valine is in extended state with minimal storic hindrance.

关 键 词：稀土配合物 甘氨酰 缬氨酸 NMR 

分 类 号：O614.33[理学—无机化学]