药用肠溶性丙烯酸树脂的合成研究  

Synthesis of enteric acrylic acid resin for drug delivery

作　　者：聂王焰[1] 周艺峰[1] 沙鸿飞[1] 

机构地区：[1]安徽大学化学化工学院,安徽合肥230039

出　　处：《安徽大学学报（自然科学版）》2003年第2期90-93,共4页Journal of Anhui University(Natural Science Edition)

摘　　要：以甲基丙烯酸与甲基丙烯酸甲酯为原料,过硫酸钾为引发剂,经溶液聚合制备出药用肠溶性丙烯酸树脂。考察了物料配比、反应温度、溶剂浓度、引发剂用量对反应的影响。Enteric acrylic acid resin for drug delivery was prepared by the solution polymerization with methacrylic acid and methyl methacrylate as raw materials and potassium persulfate as initiator. The effects of the reactant ratio, reaction temperature, solution and initiator concentration on the product properties were studied.

关 键 词：丙烯酸树脂 合成 肠溶药物 薄膜包衣材料 甲基丙烯酸 甲基丙烯酸甲脂 引发剂 溶液聚合 

分 类 号：TQ460.4[化学工程—制药化工]