双生子A型人格与高血压及血生化指标研究  

Study on relationship of type A personality of twins with hypertension and biochemical index in serum

作　　者：逄增昌[1] 翟耀明 汪韶洁[1] 彭向东[1] 薄涛[1] 闫克乐[2] 张云[1] 李晓斐[1] 苑妹[1] 

机构地区：[1]青岛市疾病预防控制中心,青岛266033 [2]河北师范大学教育科学学院

出　　处：《中国公共卫生》2003年第6期655-656,共2页Chinese Journal of Public Health

基　　金：中华医学基金(ChinaMedicalBoardCMB #0 1- 74 6 )

摘　　要：目的　了解双生子A型人格与高血压及血液生化指标的关系。方法　利用遗传流行病学方法对青岛市89对 2 4岁以上双生子 (同卵 55对 ,异卵 34对 )进行调查。并进行A型人格测试 ,以比较同卵与异卵双生子A型人格得分的相关程度、A型人格及血压的一致性。推测遗传与环境因素对A型人格的影响 ,,A型人格与高血压的关系 ,并探讨血液生化指标与A型人格的关系。结果　经KAPPA一致性检验 ,同卵 (MZ)双生子之间A型人格存在着显著的一致性 (P <0 0 0 1 ) ,而异卵 (DZ)双生子之间的一致性无显著性差异 (P =0 80 2 )。同时 ,MZ双生子之间A型人格和血压也存在显著的一致性 (P <0 0 0 1 ) ,而DZ双生子之间A型人格和血压无明显一致性 (P =0 1 0 2 )。有A型人格的双生子血压的收缩压明显高于非A型人格的双生子 (P <0 0 5)。许多生化指标与A型人格因素相关 ,但是所计算出的相关系数大都小于 0 30 ,属于弱相关。结论　MZ双生子A型人格及高血压之间存在着显著的一致性 ,而这种一致性在DZ双生子表现不明显。A型人格是高血压的危险因素之一。Objective To study on tje relationship of type A personality of twin serum biochemical index of hypertension .Methods 89 twin pairs (MZ:55,DZ:34) older than 24 in Qingdao was investigated with genetic epidemiological methods.Type A personality of the twins was tested to study the correlation of the scores in MZ and DZ twins,so that the effect of genetic and environmental factors on type A personality can be studied.The relationship between type A personality and hypertension,type A personality and some serum biochemical index were also discussed.Results Significant agreement of type A personality in MZ twins was found( P <0.001),such agreement was not found in DZ twins( P =0.802).Also agreement of type A personality and hypertension was significant in MZ( P <0.001),not significant in DZ ( P =0.102).The systolic blood pressure(SBP) was higher for twins with type A personality than non-A personality twins.Some serum biochemical index was correlated with type A personality,but most of the correlation coefficients were lower than 0.30.Conclusion Agreement of type A personality and hypertension was significant in MZ,not significant in DZ.Type A personality was a risk factor for hypertension.The correlation between type A personality and basic serum biochemical index was weak.

关 键 词：双生子 A型人格 高血压 生化指标 相关研究 

分 类 号：R181.21[医药卫生—流行病学]