性病患者血清IL-8水平的变化及其临床意义  

The changes and clinical signification of serum IL-8 level in STD patients

作　　者：李程旭[1] 邬子川[1] 高天敏[2] 王翔[1] 高燕[1] 许扬[3] 

机构地区：[1]泸州医学院微生物学与免疫学教研室,四川泸州646000 [2]泸州医学院临床医学系 [3]泸州医学院附属医院皮肤科

出　　处：《皮肤病与性病》2003年第2期1-2,共2页Dermatology and Venereology

摘　　要：目的 :判断血清白细胞介素— 8(IL— 8)在性传播疾病的诊断及疗效判断中的价值。方法　应用　ELISA　双抗体夹心法检测 40例性病患者和 40例正常人血清IL— 8水平 ,并将结果判断的特异性及敏感性与病原体培养、镜检的结果作比较。结果　性病患者血清IL— 8水平明显高于正常对照组 (P 0 0 5 ) ,其结果的特异性及敏感性均较高。结论　IL— 8在性传播疾病炎症发生过程中发挥重要作用。血清IL—By using double antibodies sandwich ELLSA,interleukin-8 concentration in serum of 40 sexually transmitted diseases and 40 mormal men were detected. The specificness and sensitiveness of this diacritical result were compared with that of pathogen cultivation and micrography. The results reveal that serum IL-8 level of STD group were obviously higher than those in mormal contrast group(P0.05),and this diagnosis had superior specificness and sensitiveness.Because IL-8 is a major chemokine ,we regard it play an important part in immurological imjury caused by STD,serum Il-8 may be considered as a potentid marker for the diagnosis of STD ,and it can also be considered as a marker of in flammatory development.

关 键 词：血清 IL-8 临床意义 白细胞介素-8 诊断 疗效 性传播疾病 检测 

分 类 号：R759[医药卫生—皮肤病学与性病学] R446.11[医药卫生—临床医学]