心肌损伤标志物在诊断急性冠状动脉综合征中的应用  

APPLICATION OF MARKER FOR MYOCARDIAL INJURY IN ACS

作　　者：冷军[1] 孙玉国[1] 朱健美[1] 宋秉跃[1] 张建[1] 

机构地区：[1]济南第四医院,250031

出　　处：《现代预防医学》2003年第3期339-340,共2页Modern Preventive Medicine

摘　　要：目的 :探讨肌红蛋白 (Myo)与心肌肌钙蛋白 T (c Tn T)检测在急性冠状动脉综合征 (ACS)中的应用。方法 :采用胶体金免疫层析技术 ,检测病人不同时间采集的血标本 ,并对 Myo与 c Tn T检测值进行分析。结果 :72例不稳定心绞痛 (U AP)患者中 ,Myo增高者占 4 7.2 % ,c Tn T增高者占 80 .6 % ;36例急性心肌梗塞 (AMI)患者中 ,Myo增高者占 6 1.1% ,c Tn T增高者占 94 .4 %。结论 :c Tn T是诊断急性冠状动脉综合征的高灵敏度、高度特异的生化检测标志物。Objective:To probe with the application of Myo and cTnT in ACS. Methods:To measure the quantitation of Myo and cTnT at different time with the technique of colloidal gold chromatograph.Resuits:Of 72 patients with UAP,there were 47.2% cases with increased Myo, and 80.6% cases with increased cTnT.Of 36 patients with AMI,there were 61.1% cases with increased Myo, and 94.4% cases with increased cTnT.Conclusion:cTnT is a high-sensitive and high-specific biochemistrical marker to diagnose ACS.

关 键 词：心肌损伤标志物 诊断 急性冠状动脉综合征 心肌肌钙蛋白T 肌红蛋白 急性心肌梗塞 不稳定心绞痛 

分 类 号：R541.4[医药卫生—心血管疾病] R542.22[医药卫生—内科学]