芎归滴丸对选择性去窦弓神经大鼠动脉压力感受反射敏感性的影响  

Effect of Xionggui Dripping Pills on Sensitivity of Baroreflex in Selective Sinoaortic Denervated Rats

作　　者：郭书英[1] 刘卫[1] 俞惠琴[1] 赵晓民[2] 高允生[2] 苏定冯[3] 

机构地区：[1]解放军第88医院,泰安市271000 [2]泰山医学院药理学教研室,泰安市271000 [3]第二军医大学药理学教研室,上海市200433

出　　处：《中国药房》2003年第6期329-331,共3页China Pharmacy

基　　金：国家新药研究基金资助项目 (98-x-05)

摘　　要：目的 :观察芎归滴丸对选择性去窦弓神经大鼠动脉压力感受反射敏感性的影响。方法 :用动态血压监测方法监测清醒的选择性去窦弓神经大鼠的动态血压 ,并用苏定冯改良的Smyth方法测定其压力感受反射敏感性的改变。结果 :芎归滴丸明显改善去窦弓神经大鼠的压力感受反射敏感性。结论 :芎归滴丸可纠正自主神经功能异常 。OBJECTIVE:To observe the effect of Xionggui dripping pills on sensitivity of baroreflex in selective sinoaortic denervated rats.METHODS:The dynamic blood pressures were monitored in selective sinoaortic denervated rats in waking stait,and the changes of baroreflex senitivity(BRS)were measured by modified SU Smyth method.RESULTS:Xionggui drip_ ping pill could improve BRS in sinus denervated rats.CONCLUSION:Since Xionggui dripping pill rectifies autonomic nerve function,it can protect target organs from damage in cardiovascular diseases.

关 键 词：芎归滴丸 选择性去窦弓神经大鼠 动脉压力感受反射敏感性 缺血性心脑血管病 

分 类 号：R285.5[医药卫生—中药学]