F波在评定糖尿病周围神经病变中的价值  

Diagnostic significance of F wave in diabetic peripheral neuropathy

作　　者：王真真 卢祖能[2] 陈文明 王镇涛[2] 曾庆杏[2] 聂传云[2] 

机构地区：[1]解放军空军广州医院神经科,广东省广州市510602 [2]湖北医科大学附属第一医院神经科,湖北省武汉市430061

出　　处：《中国临床康复》2003年第12期1784-1785,共2页Chinese Journal of Clinical Rehabilitation

基　　金：湖北省科委基金资助项目(972P1212);湖北省科技进步二等奖

摘　　要：目的探讨F波在糖尿病周围神经病(diabeticperipheralneu-ropathy,DPN)中的诊断价值。方法测定106例糖尿病(diabetesmel-litus,DM)患者和75名正常人下肢F波最短潜伏期、时限、波幅和面积,以及M波波幅和面积。结果无神经病变的DM患者30例,F波时限增宽8例,F波最短潜伏期延长4例,F/M波面积增大2例。有神经病变的DM患者76例,F波最短潜伏期均延长;F/M波波幅和F/M波面积增大;F波时限在轻型DPN患者中增宽,在重型DPN患者中未见明显异常。正常人F波最短潜伏期上限(Y)与腿长(X)的函数关系为Y=12.3+48.8X2。结论F波可作为早期诊断DPN的敏感指标,并可发现亚临床DPN。DPN患者的近、远端神经节段均可受累,近端神经损害可早于并重于远端神经。Aim To investigate the diagnostic significance of F wave in diabetic peripheral neuropathy (DPN).Methods F and M wave parameters were analyzed in 106 patients with diabetes mellitus and 75 controls,including the minimum latency,duration, amplitude and area of F wave,and the amplitude and the area of M wave.Results The minimum latency prolonged and ratio of amplitude of F/M and the ratio of the area of F/M significantly increased in the patients with DPN,the duration of F wave prolonged in the mild DPN but revealed normal in the severe ones. In the 30 patients of diabetes mellitus without neuropathy,there were 8 patients with prolonged duration of F wave,4 prolonged minimum latency of F wave,2 increased ratio of the area of F/M.In the controls, the function of upper limit of the minimum latency of F wave (Y) and leg length (X) was Y=12.3?48.8X2.Conclusion F wave could be served as sensitive means to the early diagnosis of DPN, and may detect sub clinical lesions.Both proximal and distal nerve segment could be affected in the DPN, and the proximal may be earlier and more severely involved than the distal.

关 键 词：糖尿病神经病变 电生理学 胫神经 

分 类 号：R587.2[医药卫生—内分泌] R745[医药卫生—内科学]