草酰胺桥联双核铜配合物金属胶束催化BNPP水解的动力学和机理研究  

Study on hydrolytic reaction kinetics and mechanism of BNPP catalyzed by RCu_2(H_2O)_2(ClO_4)_2 complex in micellar solution

作　　者：陈勇[1] 李延团[2] 张斌[1] 姚金华[1] 谢家庆[3] 

机构地区：[1]后勤工程学院油料应用工程系,重庆400016 [2]中国海洋大学,山东青岛266000 [3]四川大学化学学院,四川成都610064

出　　处：《化学研究与应用》2003年第3期344-347,共4页Chemical Research and Application

基　　金：后勤工程学院青年基金项目

摘　　要：合成了草酰胺桥联双核铜配合物(RCu2(H2O)2(ClO4)2)(A)和(R′Cu2(H2O)2(ClO4)2)(B)。研究了A、B与表面活性剂LSS和CTAB形成的金属胶束催化二(对硝基苯酚)磷酸二酯(BNPP)水解机理,建立了动力学模型。结果表明在25℃、pH=7的条件下,该类金属胶束对BNPP水解有催化作用,BNPP催化水解速率比其自水解速率提高1×106倍,这是由于双核铜配合物中两个铜离子的协同作用、表面活性剂胶束的浓聚效应和pH效应所致。因此含双水的草酰胺桥联双核铜配合物金属胶束是一较好的磷酸二酯水解酶的模拟模型。Oxamidobridged dinuclear copper(Ⅱ)complexes used as symmetric twocenter catalysts for the cleavage of BNPP were synthesized and characterized.Reaction kinetics and mechanism on hydrolysis of BNPP catalyzed by the dinuclear copper(Ⅱ)complexes A or B in the metallomicelle made from the complexes and different surfactant (LSS or CTAB),were investigated.The kinetic model of BNPP cleavage was proposed.The results showed that the rate(25℃,pH=7)for the catalytic hydrolysis of phosphate diester(BNPP)relative to spontaneous hydrolysis of BNPP increased about 1×106 times due to the synergistic effect of two copper ions in the complex and the local concentration effect of micelle.The study indicated the metallomicelle containing oxamidobridged dinuclear copper(Ⅱ)complex may be a potential catalyst for the hydrolysis of BNPP.

关 键 词：草酰胺桥联双核铜配合物 金属胶束 催化反应 BNPP 动力学 反应机理 二(对硝基苯酚)磷酸二酯 磷酸二酯酶 模型化合物 

分 类 号：Q556[生物学—生物化学]