4,4',6,6'-四甲氧基-2,2'二(二苯膦基)-1,1'-联吡啶(P-Phos)铑配合物催化苯乙烯不对称氢甲酰化反应  

Asymmetric hydroformylation of styrene catalyzed by (R)-P-Phos-Rh complexes

作　　者：牛渭玲[1] 陈丽[1] 胡家元[1] 陈华[1] 李贤均[1] 

机构地区：[1]四川大学化学学院,四川成都610064

出　　处：《化学研究与应用》2003年第3期414-416,共3页Chemical Research and Application

摘　　要：Rhodium complex in situ formed by (R)PPhos (4,4’,6,6’tetramethoxy2,2’bis(diphenylphosphino)1,1’bipyridine) with the available rhodium precursors are used for the asymmetric hydroformylation of styrene.Effects of total pressure,temperature and the ratio of phosphine/rhodium on catalytic activity,chemoand enantioselectivity are discussed.(R)PPhosRh shows higher activity and regioselectivity and the enantioselectivity is as much as that catalyzed by (S)BINAPRh in the in situ asymmetric hydroformylation of styrene.Rhodium complex in situ formed by (R)PPhos (4,4',6,6'tetramethoxy2,2'bis(diphenylphosphino)1,1'bipyridine) with the available rhodium precursors are used for the asymmetric hydroformylation of styrene.Effects of total pressure,temperature and the ratio of phosphine/rhodium on catalytic activity,chemoand enantioselectivity are discussed.(R)PPhosRh shows higher activity and regioselectivity and the enantioselectivity is as much as that catalyzed by (S)BINAPRh in the in situ asymmetric hydroformylation of styrene.

关 键 词：4 4’ 6 6’-四甲氧基-2 2’-二(二苯膦基)-l l’-联吡啶 铑配合物 催化 苯乙烯 不对称氢甲酰化 异构醛 

分 类 号：O625.43[理学—有机化学] O621.34[理学—化学]