顺糖氨铂(Ⅱ)的合成  

Synthesis of Nedaplatin

作　　者：孟昭力[1] 赵彦伟[1] 唐龙骞[1] 王慧才[1] 

机构地区：[1]山东大学药学院,山东济南250012

出　　处：《中国医药工业杂志》2003年第6期268-269,共2页Chinese Journal of Pharmaceuticals

摘　　要：以氯铂酸钾为原料 ,经硫酸氨铂 (Ⅱ )中间体制得抗肿瘤药物顺糖氨铂 (Ⅱ ) ,操作简便 ,总收率 46.1%。An improved process for preparing nedaplatin had been developed from K 2PtCl 6 via intermediate Pt(NH 3) 2SO 4 with an overall yield of 46.1%.

关 键 词：顺糖氨铂(Ⅱ) 抗肿瘤药 合成 

分 类 号：R971.1[医药卫生—药品]