急性心肌梗死患者血浆神经肽Y的变化及其临床意义  

The changes in plasma neuropeptide Yin acute myocardial infarction and its clinical significance

作　　者：李秀江[1] 杜玉君[1] 马丽[1] 李云阁[2] 

机构地区：[1]吉林大学第一医院,吉林长春130021 [2]中国人民解放军第四军医大学吉林军医学院,吉林吉林132000

出　　处：《吉林医学》2003年第3期236-237,共2页Jilin Medical Journal

摘　　要：目的:探讨神经肽Y(NPY)在急性心肌梗死(AMI)发生和发展中的意义。方法:用放射免疫方法测定AMI患者发病第1、3、7天血浆NPY含量变化,并与正常人作对照。结果:AMI患者发病第1、3天血浆NPY含量显著高于正常对照组(P<0.05),合并心衰者显著高于无心衰者(P<0.05)。结论:NPY可能在AMI发生和发展过程中起一定的作用;作为一项监测指标,对判断AMI患者的预后有一定的意义。Objective To investigate the clinical significance of neuropeptide Y(NPY)in acute myocardial infarction(AMI ).Method Radioimmunoassay was used to determine the plasma NPY levels in AMI.Results Plasma NPY levels were significantly higher in AMI patients than those of normal control group(P<0.05);The plasma NPY levels in AMI with heart failure were signifi-cantly higher than those of without heart failure(P<0.05).Conclusion NPY may be involved in the pathogenesis of AMI ,and NPY levels might be taken as a prognostic marker in patients with AMI.

关 键 词：急性心肌梗死 神经肽Y 心肌缺血 交感神经递质 

分 类 号：R542.22[医药卫生—心血管疾病]