350例热性惊厥的临床与脑电图观察  

Clinical and Electroencephalogram Analysis in 350 Patients with Febrile Convulsion

作　　者：郑先彪[1] 肖克娜[1] 王玲玉[1] 

机构地区：[1]华中科技大学同济医学院协和医院神经科,武汉430022

出　　处：《临床急诊杂志》2003年第3期9-10,共2页Journal of Clinical Emergency

摘　　要：目的:探讨热性惊厥(FC)的脑电图(EEG),了解FC对脑的损害及癫痫的发生率。方法:检测350例首次FC患儿的EEG,追踪随访6年,观察预后与复发情况。结果:首次EEG显示,正常275例(78.57%),轻度异常59例(16.86%),中度异常16例(4.57%)。有癫痫家族史21例(6%)。有FC家族史7例(2%)。随访结束时EEG正常219例(62.57%),轻度异常71例(20.29%),中度异常60例(17.14%)。98例(28%)只有首次FC,252例(72%)复发。18例(5.14%)并发了多动综合征。52例(14.86%)有轻度智力减退。结论:初次发作FC的患儿78.57%的EEG为正常,小于3岁和有癫痫家族史及FC家族史的患儿容易复发。反复发作惊厥可导致脑损伤或转化为癫痫。Purpose: To investigate the characters of electroencephalogram(EEG) from patients with febrile convulsion ( FC). Methods: The data of 6 years follow-up EEG from 350 patients with FC were analysed. Relationship between prognoses, rate of relapse and EEG were analysed. Results: The first evaluation of EEG displayed 275 patients of normal EEG (78. 57% ) , 59 of slightly abnormal (16. 86% ) , 16 of medial abnormal (4. 57% ).21 patients (6% ) had epileptic family history,7 patients(2%) with family history of FC among them. At the end of follow-up. There were 219 patients(62. 57% ) of normal EGG,71 (20. 29% ) of lightly abnormal,60( 17. 14% ) of medial abnormal. Single episode of FC was showed in 98 patients(28% ) , and number of recrudescent patients were 252(72% ). 18 patients (5.14% ) had complication of hyperkinetic syndrome. 52 patients( 14. 86% ) had slight cognitive dysfunction. Conclusion: Normal EEG may be showed in 78. 57% of patients with the first episode of febrile convulsion. Relapse of FC occurs mostly in patient, who is young as 3 years old and had a family history with epilepsy and FC. Relapse of convulsion leads to cerebral injury and translate to epilepsy.

关 键 词：脑电图 热性惊厥 临床观察 癫痫 

分 类 号：R720.597[医药卫生—急诊医学] R741.044[医药卫生—儿科]