生物活性陶瓷人骨复合材料的理化性能测试  

Test for Physical Chemical Properties of Bioactivity Ceramic Artificial Bone Composite Materials

作　　者：余英[1] 朱明华[1] 曾怡[1] 孙涛[1] 

机构地区：[1]四川省疾病预防控制中心,成都610041

出　　处：《职业卫生与病伤》2003年第2期88-89,共2页Occupational Health and Damage

基　　金：国家自然科学基金资助项目 (30 1 70 2 73)

摘　　要：目的　通过生物活性陶瓷人骨复合材料的理化性能的测试 ,以了解其生物相容性。方法　以Ca(OH) 2 、H3 PO4、无机氟、Ca、Si、Na .、P等金属和非金属氧化物为原料 ,采用高温、熔融、烧结、结晶、析出等方法 ,合成 5种生物活性陶瓷。以原子吸收法 ,发射光谱法和钼蓝比色法测定了 5种材料在水中Ca、P、F的溶出 ;以万能实验机测定材料的抗压强度 ;以电镜扫描观察材料的结构。结果　Ca、P、F在 5种材料中的平均溶出均比空白高。羟基磷灰石的平均抗压强度明显高于其他 4种材料。结论　不同材料Ca、P、F溶出物 ,抗压强度及结构均有所不同。Objcetive Through the test for physical chemical properties of bioactivity ceramic artificial bone composite materials, to find out the biolcompatibility.Methods Appplying calcium hydroxide, phosphoric acid, inorganic fluoride, calcium ,silicon ,sodium phosphorus etal,metallic oxide and non- metallic oxide as materials, through high temperature, melt, agglomeration, crystal, separate out, to synthesize five kinds of bioactivity ceramic. The solubility of calcium, phosphorus, fluorin of five kinds of materials in the water were determined by atomic absorption spectrometry, emission spectroscopy and molybdenum blue colorimetry. The compression strength of materials was determined by universal machine. the structure of materials was inspected by electron microscope. Results The solubility of calcium, phosphorus, fluorin of five kinds of materials in the water averagely is higher than blank test.The average compression strength of hydroxyapatite(HA) is higher than other kinds of material.Conclusion The Solubity of Calcium?Phosphorus?fluorin?Compressiun Strength and Structure of different Rimd of materials is not identical.

关 键 词：生物活性陶瓷 人骨 复合材料 理化性能 测试 生物相容性 

分 类 号：R318.17[医药卫生—生物医学工程]