高原医院不同来源CNS耐药谱的对比研究  

Study on the drug resistance against different sources of plasma-coagulase negative staphylococci in altitude hospitals

作　　者：何代平[1] 王洪斌[1] 左天林[1] 胡美玲[1] 黄云红[1] 

机构地区：[1]西藏军区总医院临床实验中心,拉萨850003

出　　处：《西南国防医药》2003年第3期257-259,共3页Medical Journal of National Defending Forces in Southwest China

摘　　要：目的 :为临床医师提供防治血浆凝固酶阴性葡萄球菌 (CNS)感染用抗生素治疗的依据。方法 :采用K -B法对不同来源 2 0 5株CNS进行 2 1种抗生素的药敏比较试验。结果 :不同来源菌株耐药率普遍为临床感染的CNS较外科环境菌株高 ,外科环境CNS较内科环境菌株高 ,差异有非常显著性或显著性 ,P <0 0 1或P <0 0 5。结论 :选择抗生素治疗时应以不易产生耐药性或耐药率相对较低的抗生素。Objective:To provide the scientific basis of using antibiotics in the treatment of plasma-coagulase negative staphylococcus(CNS)infection.Methods:K-B method was used to perform antibiotic sensitivity test on 205 strains of CNS with different sources by 21 kinds of antibiotics.Results:The drug-resistance rate clinical-infected CNS was higher than that of surgical environment CNS,and the latter was higher than that of medical environment CNS.Some of those differences were significant.Conclusion:Both no or lower drug resistance and the drug-resistance rate of clinical-infected CNS or environment CNS with remarkable or a certain degree significance should be the basis to select antibiotics for the prevention and control of CNS infection.

关 键 词：高原 医院 CNS 耐药谱 血浆凝固酶阴性葡萄球菌感染 抗生素 临床感染 环境污染 

分 类 号：R515[医药卫生—内科学] R978.1[医药卫生—临床医学]