西洋参超微粉与普通粉的溶出度及药效学比较  

Dissolution and Pharmacodynamic Comparation Between Micropowders and 100mesh Powders of Western Ginseng

作　　者：朱卫丰[1] 黄洁 傅国强 龚晓英 蔡治纲 

机构地区：[1]江西中医学院中药制药研究中心,南昌330006 [2]江西赣南海欣药业股份有限公司,赣州341000 [3]江西中医学院,2001级研究生南昌30006 [4]江中制药集团有限责任公司,南昌330077

出　　处：《江西中医学院学报》2003年第2期50-51,共2页Journal of Jiangxi College of Traditional Chinese Medicine

摘　　要：目的 :比较西洋参超微粉与普通粉 (过 10 0目 )的差异。方法 :以Rb1 为指标 ,采用HPLC法测定西洋参不同粉的溶出度百分率 ,并进行初步药效学实验。结果 :超微粉与普通粉的溶出度相似 ,初步药效学实验表明 ,超微粉 ( 2 0 μm以下占 86 % )与普通粉 ( 10 0目 )没有显著差异。结论Objection:To compare the dissolution and pharmacodynamic difference between micro-powders and 100mesh powders of Western Ginseng. Method: A HPLC UV method was developed and validated to determine Rb1 dissolution from micro powders and 100mesh powders of Western Ginseng ,primary pharmacodynamic was also studied. Results: Micro powders and 100mesh powders of Western Ginseng have similar dissolution,and pharmacodynamic effect on omuse. Conclution: Micro-powder of western Ginseng has no better pharmacodynamic effect.\;

关 键 词：西洋参 超微粉 普通粉 溶出度 药效学 比较 实验 

分 类 号：R282.71[医药卫生—中药学]