直缘乌头中新的C_(19)-二萜生物碱的结构研究  

New C_(19)-Diterpenoid Alkaloids from the Roots of Aconitum transsecutum

作　　者：陈东林[1] 简锡贤[1] 陈巧鸿[1] 王锋鹏[1] 

机构地区：[1]四川大学华西药学院天然药化教研室,成都610041

出　　处：《化学学报》2003年第6期901-906,共6页Acta Chimica Sinica

基　　金：教育部高等学校博士点基金 (No.2 0 0 1 0 61 0 0 4 7)资助项目

摘　　要：从直缘乌头 (AconitumtranssectumDiels .)根中分离得到 4个新的乌头碱型C19- 二萜生物碱 .由光谱法 (IR ,1HNMR ,13 CNMR ,2D NMR ,MS)确定其结构为 :8 O 乙基滇乌碱 (8 O ethylyunaconitine) (1)、去氮乙基查斯曼宁 (N deethylchasmanine) (2 )、直缘乌碱丁 (transconitineD) (3 )和直缘乌碱戊 (transconitineE) (4 ) .Four new C-19-diterpenoid alkaloids, 8-O-ethylyunaconitine (1), N-deethyl chasmanine (2), transconitine D (3) and transconitine E (4), were isolated from the roots of Aconitum transsectum Diels. together with 11 known norditerpenoid alkaloids, yunaconitine, indaconitine, vilmorrianine A, vilmorrianine C, crasscualine A, geniconitine, chasmanine, 8-deacetylyunaconitine, talatisamine, 14-acetyltalatisamine and chasmaconitine. Their structures were assigned on the basis of spectral data (IR, H-1 NMR, C-13 NMR, 2D-NMR and MS).

关 键 词：直缘乌头 C19-二萜生物碱 结构 直缘乌碱戊 去氮乙基查斯曼宁 直缘乌碱丁 植物药 分离 

分 类 号：O629[理学—有机化学]