青霉素G亚砜对-甲氧基苄基酯的制备  被引量:13

Preparation of Penicillin G Sulfoxide Ester

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作  者:陈刚[1] 石鸿昌[1] 王歆燕[1] 樊新印[1] 

机构地区:[1]清华大学化学系,北京100084

出  处:《应用化学》2003年第7期706-708,共3页Chinese Journal of Applied Chemistry

摘  要:The preparation procedure of benzylpenicillin sulfoxide p-methoxybenzyl ester by esterificating penicillin G potassium salt and following oxidizing the corresponding benzylpenicillin ester is described. The method using the only reactive solvent minimizes the kinds of solvents and decreases the volume of solvents, which facilitates technical procedures and reduces the cost.The preparation procedure of benzylpenicillin sulfoxide p-methoxybenzyl ester by esterificating penicillin G potassium salt and following oxidizing the corresponding benzylpenicillin ester is described. The method using the only reactive solvent minimizes the kinds of solvents and decreases the volume of solvents, which facilitates technical procedures and reduces the cost.

关 键 词:青霉素亚砜酯 合成 

分 类 号:O626.32[理学—有机化学] TQ465.1[理学—化学]

 

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