白细胞减少症皮窗细胞反应的临床研究  

Clincal study of skin-window cells response in patients with leukopenia

作　　者：张晓群[1] 王友光[1] 陈波[1] 肖焰[1] 孙守纯[1] 

机构地区：[1]黄石市中心医院血液科,湖北黄石435002

出　　处：《临床血液学杂志》2003年第4期165-167,共3页Journal of Clinical Hematology

摘　　要：目的 :分析研究白细胞减少症患者皮窗细胞反应的变化与机体抗感染防御能力的关系。方法 :对未经治疗的原发性白细胞减少症患者 3 8例及正常对照者 3 0例进行皮窗实验 ,并比较患者中白细胞被激发者与不被激发者之间以及白细胞减少症治疗前后皮窗细胞反应的变化。结果 :3 8例患者中 ,2 3例 ( 60 .5 % )患者皮窗反应结果均相似 ,15例 ( 3 9.5 % )患者皮窗细胞反应弱于正常对照组 (P <0 .0 1) ;白细胞被激发者与不被激发者之间皮窗细胞反应差异无显著性意义 ;15例皮窗细胞反应弱的白细胞减少症患者治疗前后的皮窗细胞变化中 ,9例改变明显 ,6例无明显改变。结论 :白细胞减少症皮窗渗出物细胞变化可直接反应机体抗感染防御能力 。Objective:To investigate the relationship between change of skin-window cells response and the capability of anti-infection in patients with leukopenia.Method:Skin-window test was studied in 38 patients with primary leukopenia before teartment,15patients with primary leukopenia after treatment and 30 healthy controls.Their skin window response functions were also compared.Result:Compared with healthy controls, 23( 60.5%) of 38 patients with primary leukopenia had same skin-window cells response.There was no significant difference (P> 0.05) in leucocytic provocative reaction.Compared with patients before treatment,9 of 15 patients were significantly different,6 were not significantly different.Conclusion:The change of skin-window cells response may predict the capability of anti-infection in patients with leukopenia.It was not certained that the capability of anti-infection would low in patients with leukopenia.

关 键 词：白细胞减少症 白细胞功能 皮窗实验 皮窗渗出物细胞反应 

分 类 号：R557[医药卫生—血液循环系统疾病]