紫外分光光度法测定盐酸丁卡因甘油溶液中盐酸丁卡因含量  

Content determination of tetracaine hydrochloride in glycerin solution of tetracaine hydrochloride by ultraviolet spectrophotometry

作　　者：高红旺[1] 张秀荣[1] 朱军[2] 许英爱[1] 

机构地区：[1]第四军医大学吉林军医学院药学教研室，吉林吉林132013 [2]解放军第456医院药剂科，山东济南250031

出　　处：《第四军医大学吉林军医学院学报（86813X）》2003年第2期80-81,共2页Journal of Jilin Military Medical College Fourth Military Medical University

摘　　要：目的 探讨紫外分光光度法测定盐酸丁卡因甘油溶液中盐酸丁卡因的含量方法。方法 以紫外分光光度法测定盐酸丁卡因甘油溶液中盐酸丁卡因的含量，并与永停滴定法测定的结果进行比较。结果 在波长310nm处有最大吸收，回归方程为A＝0．07510C+0．00369，r＝0．9999；平均回收率为99．81％，平均标示含量为98．46％，RSD＝1．15％。结论 该法操作较永停法简便，结果无显著性差异。Objective To analyse the method for content determination of tetracaine hydrochloride in glycerin solution of tetracaine hydrochloride by ultraviolet spectrophotometry.Mehtods The content of tetracaine hydrochloride in glycerin solution of tetracaine hydrochloride was determined by ultraviolet spectrophotometry and then its results were compared with those of dead stop titration.Results The maximal absorption of tetracaine hydrochloride was at the wavelength of 310nm,and its regression equation was A=0...

关 键 词：盐酸丁卡因甘油溶液 盐酸丁卡因 含量测定 紫外分光光度法 

分 类 号：R971.2[医药卫生—药品] R927.2[医药卫生—药学]