固载相转移催化剂催化合成1,4-二氢-2,6-二甲基-3,5-吡啶二甲酸二乙酯  

Synthesis of Diethyl 1,4-dihydro -2,6-dimethyl-3,5-pyridinedicarboxylate with Polymer-supported Phase Transfer Catalyst

作　　者：陆绍荣[1] 

机构地区：[1]桂林工学院材料与化学工程系,广西桂林541004

出　　处：《化学研究》2003年第2期50-52,共3页Chemical Research

基　　金：广西自然科学基金资助项目.

摘　　要：采用三相相转移催化剂(四丁基溴化铵-聚苯乙烯树脂),以乙酰乙酸乙酯和六次甲基四胺为原料,合成了1,4-二氢-2,6-二甲基-3,5-吡啶二甲酸二乙酯,探讨了反应条件对产物收率的影响,并对产品结构进行了红外光谱及元素分析表征.A new process has been developed to synthesize diethyl 1,4dihydro2,6dimethyl 3,5pyridinedicarboxylate from acetoacetic ester and hexamethylenetetramine by catalysis of triphase transfer catalyst (PSTBAB), and the reaction conditions on the yield of the product were studied. The structure of the product was confirmed by elemental analysis and IR.

关 键 词：相转移催化剂 催化合成 1 4-二氢-2 6-二甲基-3 5-吡啶二甲酸二乙酯 乙酰乙酸乙酯 六次甲基四胺 表征 二氢吡啶类化合物 

分 类 号：O626.32[理学—有机化学]