正交试验法优选白芍中芍药苷的提取工艺研究  

Study on Optimum Extraction Process for Paeoniflorin in Paeonia lactiflora Pall by Orthogonal Design

作　　者：吴悟贤[1] 李生才[1] 牛之猛[1] 

机构地区：[1]北京理工大学新医药开发研究中心,北京100081

出　　处：《时珍国医国药》2003年第7期392-393,共2页Lishizhen Medicine and Materia Medica Research

摘　　要：目的 :以白芍中主要成分芍药苷的含量为指标 ,优选提取最佳工艺条件。方法 :采用正交试验法进行优选。结果 :以70 %的乙醇回流 ,调节 p H至 6～ 7,上 AB- 8大孔吸附树脂层析后得到的芍药苷含量均在 40 %以上。结论Objective:To optimize the optimum extraction process for paeoniflorin in Paeonia lactiflora Pall by using content of the paeoniflorin as the index.Methods:The extraction process was optimized by the orthogonal design.Results:The optimum extraction colophony, and the content of paeoniflorin can be up to 40%.Conclusion:The separated effect of paeoniflorin is very preferable by using this technology, furthermore, the manipulation is simple and quick.

关 键 词：白芍 芍药苷 高效液相色谱 正交试验法 

分 类 号：R284.2[医药卫生—中药学]