四(二乙胺基)溴化鏻的合成及用于相转移催化Halex反应  

Synthesis of Tetrakis(diethylamino)phosphonium Bromide and Its Application as PTC in Halex Reaction

作　　者：赵文娟[1] 李亚明[1] 张华[1] 万相见[1] 那强[1] 

机构地区：[1]大连理工大学精细化工国家重点实验室,辽宁大连116012

出　　处：《精细化工》2003年第7期407-408,448,共3页Fine Chemicals

摘　　要：四(二乙胺基)溴化鏻(TPB)是制备含氟芳香族化合物的一种新型相转移催化剂。以PCl3作原料经季鏻化、氨解、中和、烷基化4步反应合成了TPB,反应总收率41%,w(TPB)=90%。产物由31PNMR、1HNMR、MS进行了结构确证。并将该催化剂应用于Halex反应制备对氟硝基苯,初步考察了其催化效果,收率62%。Tetrakis(diethylamino)phosphonium bromide(TPB) was a novel phase transfer catalyst used to prepare fluorinated aromatic compounds.TPB was synthesized from PCl3 through fourstep reactions:quaternization,amination,neutralization and alkylation.The yield was up to 41%,w(TPB)=90%.The structure of TPB was characterized by31PNMR,1HNMR and MS.It was used in Halex reaction to prepare pnitrofluorobenzene with 62% yield and its catalytic capability was studied.

关 键 词：四(二乙胺基)溴化鳞 相转移催化剂 对氟硝基苯 

分 类 号：O627.5[理学—有机化学]