胃癌中ER、PR表达及其与癌转移的研究  

Relationship Between ER,PR Expression and Tumor Histology Type and Metastasis in Gastric Cancer

作　　者：李金龙 杨苏敏[2] 李青[2] 

机构地区：[1]潞安矿务局医院,046000 [2]长治医学院病理学教研室

出　　处：《长治医学院学报》2003年第2期88-90,共3页Journal of Changzhi Medical College

摘　　要：目的 :探讨胃癌ER、PR表达及其与癌转移的关系。方法 :应用S -P免疫组化方法 ,观察1 0 0例胃癌中ER、PR表达。结果 :ER、PR阳性表达分别为 5 0 %和 44.0 % ,均与细胞分化程度 ,组织学类型有关。淋巴结无转移者阳性表达比淋巴结伴有癌转移者高 ,差异有显著性 (P <0 .0 1 )。结论 :ER和PR阳性表达有高度一致性 ,二者的检测对胃癌的预后判断有一定临床意义。Objective:To study the estrogen receptor(ER),progestogen receptor(PR) expression and metastasis in gastric cancer.Methods:100 cases of gastric cancer were studied by immunohistochemical staining (S-P method) to observe the realtionship between ER,PR expression and tumor histology type and metastasis.Results:The positive rates of ER and PR expression were 50.0% and 44.0% respectively that had correlation with cell differtiation and type of histology;the positive rates of lymph nodes with no melastasis were signifcantly higher than that in the lymph nodes with metaslasis (P<0.01).Conclusion:The positive rates of Er and PR expression have high consistency.Expression of ER and PR have a clinical signaficance for evaluating prognosis of gastric cancer.

关 键 词：胃癌 ER PR 免疫组织化学 

分 类 号：R392.11[医药卫生—免疫学]