早产胎膜早破孕妇血清中白细胞介素6含量变化  

Changes of interleukin-6 levels in maternal serum in preturm birth patients with premature rupture of membranes

作　　者：梁小勤[1] 陈瑞玲[1] 

机构地区：[1]广东省深圳市宝安区人民医院,广东深圳518101

出　　处：《河北医学》2003年第6期489-491,共3页Hebei Medicine

摘　　要：目的 :探讨早产胎膜早破孕妇血清中白细胞介素 6 (interleukin - 6 ,IL - 6 )含量与绒毛膜羊膜炎的关系。方法 :采用酶联免疫吸附法 (ELISA)对 30例早产胎膜早破及 2 0例正常孕妇 (对照组 )血清中IL - 6水平进行检测 ,同时行胎膜病理检查。结果 :早产胎膜早破绒毛膜羊膜炎孕妇血清中IL- 6含量明显高于非绒毛膜羊膜炎者 (P <0 .0 1)。结论 :早产胎膜早破血清IL - 6升高与绒毛膜羊膜炎有关 ,母血IL - 6水平可作为早产胎膜早破组织绒毛膜羊膜炎预测指标。Objective: To study the change and clinical significance of maternal serum interleukins-6(IL-6) levels in preturm birth patients with chorioamnionitis and premature rupture of membrane (PROM). Methods: 30 pregnant women with preturm birth premature rupture of membrane were included in study group and 20 normal pregnant women as control. Maternal serum IL-6 were measured by enzyme-labeled immunosorbent assay(ELISA). Chorioamnionitis was diagnosed histologically. Results: The serum of maternal IL-6 with histotogical chorioamnionitis showed a significant increased than those chorioamnionitis (P<0.01). Conclusion: IL-6 in maternal serum is valuable clinical indices for indentification of chorioamnionitis in patients with PROM. Measurement of maternal serum IL-6 is a marker for screening histological chorioamnionitis PROM at term.

关 键 词：早产 胎膜早破 孕妇 血清 白细胞介素6 含量 

分 类 号：R714.21[医药卫生—妇产科学]