胎儿肺泡上皮和气血屏障的电镜观察  

TRANSMISSION ELECTRON MICROSCOPIC OBSERVATION OF ALVEOLAR EPITHELIUM AND BLOOD-AIR BARRIER OF HUMAN FETUS

作　　者：薄爱华[1] 夏苓[1] 李海峰[1] 安玉兰 张竟时[1] 何丁[1] 戴洁[1] 祁晓莉[1] 刘洪莲[1] 

机构地区：[1]张家口医学院电镜室,张家口075029 [2]张家口市第三医院

出　　处：《解剖学报》1992年第1期102-105,共4页Acta Anatomica Sinica

摘　　要：为阐明不同胎龄肺泡表面上皮和气血屏障的发育状况,对24例受精龄为14～40周的人胎肺脏,进行透射电镜观察。胎龄19周时,即可辨认肺泡Ⅰ型上皮细胞和气血屏障。图像分析表明,气血屏障的厚度,随胎龄的增长而变薄。Ⅱ型肺泡上皮细胞,在胎龄20周后逐渐分化,22周时胞质内出现板层小体,小体的截面积随胎龄而增大。本文着重对气血屏障及Ⅱ型上皮细胞的形态变化进行了讨论。In order to investigate the development of the lung, the ultrastructure of alveolar epithelium from 24 human fetuses of 14-40 weeks in gestation age were observed. The pneumocyte type Ⅰ and blood-air barrier were present at 19 weeks. The thickness of blood-air barrier was measured by image analyzer. The results showed that the blood-air barrier gradually attenuated with the gestation age. After 20 weeks, pneumocyte type Ⅱ gradually differentiated. The lamellar bodies were first observed at 22 weeks. The section area of the lamellar body increased also with the age. The developmental changes of blood-air barrier and pneumocyte type Ⅱ and their significance were discussed.

关 键 词：肺泡 肺泡上皮 气血屏障 胎儿 

分 类 号：R329.435[医药卫生—人体解剖和组织胚胎学]