不同类型白内障晶状体上皮细胞密度分析  

Analysis of lens epithelial cell density among different types of cataracts

作　　者：张虹[1] 李贵刚[1] 谢二娟[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院眼科,湖北武汉430030

出　　处：《眼科新进展》2003年第4期245-247,共3页Recent Advances in Ophthalmology

摘　　要：目的 研究人晶状体上皮细胞密度与白内障类型的关系,探讨晶状体上皮细胞病变对白内障发病的意义。方法 随机收集60例白内障手术患者的晶状体前囊膜,固定后铺片,行HE染色后测定上皮细胞密度。按不同类型白内障进行分组,分析晶状体上皮细胞密度与白内障类型及患者年龄以及性别的关系。结果 先天性白内障组晶状体上皮细胞密度最高,平均(4316.63±479.65)个·mm^(-2),平均年龄(9.88±8.16)岁;其次为外伤性白内障组,平均细胞密度(3899.81±537.00)个·mm^(-2),平均年龄(29.43±19.66)岁;并发性白内障组平均细胞密度(3838.46±454.72)个·mm^(-2),平均年龄(54.22±7.63)岁;老年性白内障组平均细胞密度(3740.45±526.33)个·mm^(-2),平均年龄(67.39±11.08)岁。老年性白内障晶状体上皮细胞密度50～59岁组、60～69岁组、70～79岁组、80岁以上组均数间差异无显著性意义,男女患者间差异无显著性意义。结论 白内障晶状体上皮细胞密度与白内障类型有关;老年性白内障晶状体上皮细胞密度与患者年龄及性别无明显相关。Objective To investigate the difference of lens epithelial cell density among various types of cataracts. Methods Sixty cases anterior lens capsules of patients with different types cataract were randomly collected and spreaded on slides , fixed and stained with hematoxuline-eosine. Cell densities were determined by computer imagine analysis system. Results The congenital cataract had the highest cell deasity with (4 316.63 + 479.65) cells -mm-2; Traumatic cataract was (3 899.81 +537.00) cells mm-2;Complicated cataract was (3 838. 46 + 454. 72) cells mm-2 and senile cataract was (3 740. 45 + 526. 33) cells -mm-2. There was a significant difference between congenital cataract and complicated or senile cataract , traumatic and senile cataract. While there was no significant difference between congenital and traumatic group or between complicated and senile cataract ; No significant difference between male and female. No significant correlation was found between cell density and patients age of senile cataract. Conclusion The lens epithelial cell density is related to the types of cataracts; But leas epithelial cell density have no relation with the age of senile cataract.

关 键 词：白内障 晶状体上皮细胞 细胞密度 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学] R776.1[医药卫生—基础医学]