心室肌细胞L型钙离子通道研究  

Research on L-type Calcium Channels of Ventricular Myocytes

作　　者：陈波[1] 张培华[1] 马季骅[1] 

机构地区：[1]武汉科技大学医学院,湖北武汉430080

出　　处：《武汉科技大学学报》2003年第2期209-211,共3页Journal of Wuhan University of Science and Technology

摘　　要：L型钙通道电流是心肌细胞动作电位的重要组成部分,亦是细胞内钙释放的重要触发因素。通过研究分析表明,氧反常早期L型钙通道功能异常是导致细胞内钙超载的重要启动因素,而L型钙通道功能异常是诱发折返性心律失常的重要机制。Ltype Ca2+ channel current is the important component of AP of myocardial cell and the important trigger for the release of inner calcium.It is found that the functional abnormity of Ltype Ca2+ channel in the early oxygen paradox is the important factor resulting in Ca2+overloaded inside cells.,and the functional abnormity of Ltype Ca2+ channel contributes greatly to arrhythmia.

关 键 词：L型钙通道 钙超载 NA^+/CA^2+交换 氧反常 心律失常 

分 类 号：R543.7[医药卫生—心血管疾病]