蒲黄配方颗粒质量标准的研究  

Study on quality standard for Puhuang Dispensing Granule

作　　者：刘斌[1] 王晓强[1] 王伟 

机构地区：[1]北京中医药大学中药学院,北京100102 [2]北京康仁堂药业有限责任公司,北京102407

出　　处：《中成药》2003年第8期624-626,共3页Chinese Traditional Patent Medicine

基　　金：国家自然科学基金资助项目 (No .3 0 0 0 0 2 2 0 )

摘　　要：目的 :对蒲黄配方颗粒进行质量标准研究。方法 :采用薄层色谱法对蒲黄配方颗粒进行定性鉴别 ;采用高效液相色谱法对蒲黄配方颗粒中的异鼠李素 3 O 新橙皮糖苷和香蒲新苷进行含量测定。结果 :异鼠李素 3 O 新橙皮糖苷和香蒲新苷的线性范围分别为 0 .4～ 1.2 1μg和 0 .4 2～ 1.2 5 μg ,平均回收率分别为 98.88%和 99.6 8%。 结论 :方法可行、重复性好 ,能有效地控制蒲黄配方颗粒的质量。Objective: To study the quality standard for Puhuang Dispensing Granule (Pollen Typhae). Methods : Puhuang Dispensing Granule was identified by TLC and isorhamnetin-3-O-neohesperidoside and typhaneoside in Puhuang Dispensing Granule were determined by HPLC. Results : The linear relationship was at the range of 0.4～1.21μg for isorhamnetin-3-O-neohesperidoside and 0.42～1.25μg for typhaneoside, respectively. The average recovery was 98.88% for isorhamnetin-3-O-neohesperidoside and 99.68% for typhaneoside, respectively. Conclusion : The method is available with a good reproducibility and can control the quailty of Puhuang Dispensing Granule.

关 键 词：蒲黄 配方颗粒 异鼠李素-3-O-新橙皮糖苷 香蒲新苷 质量标准 

分 类 号：R286.0[医药卫生—中药学]