磁共振谱成像(MRSI)技术的研究进展  

Overview of magnetic resonance spectroscopic imaging(MRSI) technology

作　　者：钱勇先[1] 黄敏[1] 林家瑞[1] 

机构地区：[1]华中科技大学生物医学工程研究所,湖北武汉430074

出　　处：《国外医学（生物医学工程分册）》2003年第4期145-150,共6页Foreign Medical Sciences(Biomedical Engineering Fascicle)

基　　金：国家自然科学基金资助项目 (30 0 70 2 2 6 )

摘　　要：磁共振谱成像 (MRSI)在临床诊断中的作用越来越大。目前 ,最有效的快速谱成像法有回波平面法、螺旋轨迹法和阵列采集法。但是 ,这些 MRSI方法的数据采集时间仍然很长 ,速度有待于进一步提高。抑水抑脂脉冲序列基本定型 ,改进的余地不大。在定量的谱分析方面 ,已经实现分析自动化。谱参数估计方法基本完善 ,但在强基线信号时参数估计方法有待于深入研究。目前 ,磁共振谱的图像重建方法局限在 FFT或网格化后的 FFT,这些方法比较简单、快速 ,但也局限了采样脉冲序列 (采样轨迹 )的大胆设计。期望研究出速度更快的 MRSI数据采集脉冲序列。Magnetic resonance spectroscopic(MRSI) plays a more and more important role in clinical application.Up to now,the method based on echo planar,spiral trajectories or array detectors is the fastest method in MRSI,but the acquisition time is too long and the speed must be enhanced.Water and fat suppression pulse have fall into patterns and have no much more improvement.In the area of spectroscopic quantitative analysis,automatic analysis has been realized.The estimation method of spectroscopic parameters is perfect,but the method in the present of strong base signal still must be improved.The image reconstruction methods of MRSI use FFT or gridding FFT mainly.Both are simple and fast,but they also limit the design in acquisition pulses(trajectories).The data acquisition plus with faster speed in MRSI is expected.

关 键 词：磁共振谱成像 快速成像 图像重建 谱分析 

分 类 号：R310[医药卫生—基础医学]