氯氮平与利培酮对精神分裂症患者血糖的影响  

The effect of clozapine and risperidone on blood sugar of patients with schizophrenia

作　　者：樊彩联[1] 雷莹[1] 王康建[1] 张露莹[1] 

机构地区：[1]陕西省西安市精神卫生中心,710061

出　　处：《山东精神医学》2003年第3期131-132,共2页Shangdong Archives of Psychiatry

摘　　要：目的　探讨氯氮平与利培酮对精神分裂症患者血糖的影响。方法　对 6 0例精神分裂症患者分为氯氮平组和利培酮组 ,进行为期 8周的治疗 ,采用自身对照 ,比较用药前后血糖浓度。结果　氯氮平组治疗后血糖浓度显著升高 (P <0 .0 5 ) ;利培酮组治疗后血糖无明显变化 (P >0 .0 5 )。结论　氯氮平可引起精神分裂症患者血糖升高 ;Objective To detect the effect of clozapine and risperidone on blood sugar of schizophrenia.Methods Sixty patients with schizophrenia were divided into clozapine group and risperidone group for 8 weeks.The blood sugar was evaluated before and after treatment.Results After treatment,the blood sugar of clozapine group rose significantly ( P <0.05),and that of risperidone group had no significant change ( P >0.05).Conclusion Clozapine could cause blood sugar of schizophrenic patients rise.Risperidone had no significant effect on blood sugar.

关 键 词：氯氮平 利培酮 精神分裂症 血糖 抗精神病药物 

分 类 号：R971.4[医药卫生—药品] R749.3[医药卫生—药学]