Consecutive Reaction of Bis[2,2,2-trifluoroethyl]phosphite.Onepot Synthesis of Substituted 3-Cyano-β,γ-unsaturated Nitriles with Exclusive or Predominant E-Selectivity  

作　　者：沈延昌 张玉明 

机构地区：[1]State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences,Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2003年第7期907-909,共3页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China(No.29972046)and Chinese Academy of Sciences.

摘　　要：The consecutive reaction of bis [2,2,2-trifluoroethyl ] phosphite and its application to the one-pot synthesis of 3-cyano-β,γ-un-saturated nitriles with exclusive or predominant E-selectivity (E:Z = 100-85:0-15) and excellent yields (94%-99%) are described.The consecutive reaction of bis [2,2,2-trifluoroethyl ] phosphite and its application to the one-pot synthesis of 3-cyano-β,γ-un-saturated nitriles with exclusive or predominant E-selectivity (E:Z = 100-85:0-15) and excellent yields (94%-99%) are described.

关 键 词：consecutive reaction one-pot synthesis 3-cyano-β γ-unsaturated nitrile bis[2 2 2-trifluoroethyl]phosphite E-selec-tivity 

分 类 号：O621[理学—有机化学]