白虎追风丸对佐剂性关节炎大鼠血液中氧自由基的影响  

Effect of Baihu Zhuifeng Wan on the Free Radical in Rats with Rheumatoid Arthritis

作　　者：施旭光[1] 黄兆胜[1] 高汉森[1] 

机构地区：[1]广州中医药大学中药学院,广州510405

出　　处：《中国中医药信息杂志》2003年第7期21-22,共2页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的:探讨白虎追风丸对佐剂性关节炎(AA)大鼠的治疗作用及其作用机理。方法:随机对照观察白虎追风丸组、对照组大鼠关节肿胀情况及血液中脂质过氧化物(LPO)、谷胱甘肽过氧化物酶(GSH-PX)、超氧化物歧化酶(SOD)的含量和活性。结果:白虎追风丸不仅抑制足跖肿胀,而且降低AA大鼠过高的LPO水平,同时还使其过低SOD和GSH-PX活性增高或恢复正常。结论:白虎追风丸对AA大鼠有抗炎和抗氧化作用。Objective:To explore the effect and mechanism of Baihu Zhuifeng Wan (BZW) on rats with rheumatoid. Method:The activities and contests of LPO, SOD and GSH-PX in blood in BZW group and control group were observed. Results:The result indicated that BZW has anti-inflammatory effect on rheumatoid artritis. It could decrease serum lipid peroxides and increase superoxide dismutase and glutathione peroxidase level. Conclusion:BZW has anti-inflammatory effect and anti-oxidation effect on rats with rheumatoid arthritis.

关 键 词：白虎追风丸 佐剂性关节炎 大鼠 血液 氧自由基 中医药治疗 脂质过氧化物 谷胱甘肽过氧化物酶 

分 类 号：R259.932.2[医药卫生—中西医结合] R285.5[医药卫生—中医内科学]