皂甙类化合物解簇集行为的研究  

Deaggregation Behavior of Saponin Compounds

作　　者：计国桢[1] 张广明[1] 唐靓[1] 蒋锡夔[1] 

机构地区：[1]中国科学院上海有机化学研究所,上海200032

出　　处：《化学学报》2003年第7期970-975,共6页Acta Chimica Sinica

基　　金：国家自然科学基金(Nos.29392201;29672406);中国科学院九五基础性重大项目(KJ-951-A1-503-01)

摘　　要：用荧光光谱方法研究了皂甙类化合物在φ=0.60 DX-H_2O溶液中对探针Np-8-Ch簇集体的解簇集行为,讨论了皂甙类化合物结构与解簇集能力间的关系.并结合细胞粘附实验,探讨了此类化合物解簇集能力与它们药物功能之间的联系.The deaggregation behavior of saponin compounds was studied in Phi = 0.60 DX-H2O solution by fluorescence spectroscopy. The relationship of stricture and deaggregating abilities of saponin compounds has been discussed. In comparison with the results of cell adhesion experiments, the relationship of the deaggregating abilities for saponin compounds with.:their biological behavior has been discussed.

关 键 词：皂甙类化合物 解簇集行为 荧光光谱法 结构 解簇集能力 药物功能 中草药 

分 类 号：O621[理学—有机化学]