半枝莲提取工艺的研究  

Study on extraction process of Scutellaria barbata

作　　者：邸多隆[1] 刘丽春[2] 刘晔玮[3] 刘霞[1] 蒋生祥[1] 

机构地区：[1]中国科学院兰州化学物理研究所 [2]甘肃省人民医院药剂科,兰州730000 [3]河西学院化学系,甘肃张掖734000

出　　处：《中成药》2003年第7期530-532,共3页Chinese Traditional Patent Medicine

基　　金：中国科学院兰州化物所"知识创新工程"重大基础性研究项目基金资助。

摘　　要：目的 :用正交实验法优选半枝莲提取工艺。方法 :以浸膏得率、总黄酮和野黄芩苷提取率为评价指标 ,选择乙醇浓度 (% )、加醇量 (倍 )、提取时间 (h)为考察因素 ,利用正交试验L9(34)确定了醇提取半枝莲的工艺。结果 :最佳工艺条件为 75 %乙醇 10倍量提取 2 .0h ,共提取 2次。结论 :平均乙醇浸膏得率为 13.6 % ,总黄酮和野黄芩苷提取率分别为91.7%和 78.4 % (n =3)。Objective:To study the optimum ethanol extraction process. Methods: The extraction rate of extractum and total flavonoids as well scutellarin was choosen as the assessment index. The optimum ethanol extraction process was selected with the orthogonal design. Results: The optimum ethanol extraction process conditions follow as: adding 10 fold of 75% ethanol, extracting for 2.0h and twice in all. Conclusion: The average extraction rate of extractum and total flavonoids as well scutellarin was 13.6%, 91.7%, 78.4%(n=3), respectively.

关 键 词：半枝莲 浸膏 总黄酮 野黄芩苷 正交试验 

分 类 号：R284.2[医药卫生—中药学]