增生消胶囊对大鼠慢性萎缩性胃炎的防治作用研究  

Effects of prevention and treatment on atrophic gastritis in rats with Zengshengxiao Capsules

作　　者：裴林[1] 李佃贵[2] 蔡春江[2] 扈国杰[2] 李振彬[3] 

机构地区：[1]河北医科大学中医药研究院,石家庄050031 [2]河北医科大学,石家庄050011 [3]白求恩国际和平医院,石家庄050071

出　　处：《中成药》2003年第7期567-569,共3页Chinese Traditional Patent Medicine

基　　金：河北省科学技术厅科学技术研究与发展项目 :( 990 2 0 4)

摘　　要：目的 :观察增生消胶囊对大鼠慢性萎缩性胃炎的防治作用 ,探讨其作用机理。方法 :采用主动免疫加胆汁、热水灌胃的综合方法模型、醋酸扭体法。结果 :增生消胶囊可改善胃粘膜血流量 ,提高 pH值抑制炎细胞浸润、腺体萎缩和不典型增生 ,并有明显的镇痛作用 ,无明显毒副作用。结论 :增生消胶囊对大鼠慢性萎缩性胃炎具有较好的防治作用。Objective:To study the protective and therapeutic effects of Zengshengxiao Capsules (ZSX) on atrophic gastritis in rats. Methods: The model was established by methods of active immunity and gastrogavage with bile and hot water. The method of acetic acid writhing was used. Results: (ZSX) had actions of promoting the blood flow of gastric mucosa, increasing in pH, inhibiting inflammatory cell infiltration, glandular atrophia and atypical hyperplasia. It also had action of alleviating pain. There were no toxic and side effects. Conclusion: (ZSX) had remarkably preventive and therapeutic effects on atrophic gastritis of rats.

关 键 词：增生消胶囊 大鼠 慢性萎缩性胃炎 中医药治疗 

分 类 号：R285.6[医药卫生—中药学]