居室内尘螨抗原浓度与螨过敏常年性变应性鼻炎的关系  

The relationship between the density of house dust mite allergens in bedroom and the attacks of allergic rhinitis

作　　者：邢志敏[1] 栗建林[2] 王旻[1] 王更慧 安淑兰[1] 于德林[1] 

机构地区：[1]北京大学人民医院耳鼻咽喉科,北京100044 [2]北京市劳动卫生职业病防治研究所

出　　处：《临床耳鼻咽喉科杂志》2003年第9期547-549,共3页Journal of Clinical Otorhinolaryngology

摘　　要：目的 :了解螨过敏常年性变应性鼻炎 (PAR)患者发病与居室内螨抗原水平的关系。方法 :分别收集35例螨过敏PAR患者 (PAR组 )、30例健康者 (对照组 )居室内床垫、被褥、沙发和枕头等尘螨积聚部位的灰尘 ,称重后 ,用抗原抗体酶联免疫法半定量测定室尘螨抗原 (Derp1)和粉尘螨抗原 (Derf1)的含量。结果 :对照组居室内Derp1、Derf1抗原水平明显高于PAR组 ,差异均有显著性意义 (均P <0 .0 5 ) ;两组居室内 ,Derp1与Derf1浓度差异均无显著性意义 (均P >0 .0 5 )。结论 :螨过敏PAR患者是否发病虽与螨抗原水平有关 ,但关键取决于个体特异性。Objective:To investigate the relationship between the density of house dust mites allergens in bedroom and the attacks of allergic rhinitis in patients sensitive to mite.Method:Seventy-five houses(35 patients with allergic rhinitis and 30 healthy controls )were visited for dust sampling from mattresses, sofas, bedings and pillows. Der p 1 and Der f 1 levels were measured by ELISAs.Result:Der p 1 and Der f 1 levels in healthy control group were significantly higher than levels in patient group(P< 0.05).Conclusion:The amount of mite allergens might not be the determining factor for allergic rhinitis sensitization.

关 键 词：尘螨 变应性鼻炎 常年性 室内环境 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]