N-甲基吗啉的合成  

Synthesis of N-Methylmorpholine

作　　者：张想竹[1] 张继昌[1] 吴明书[1] 

机构地区：[1]安阳大学化工系,安阳455000

出　　处：《应用化学》2003年第9期917-918,共2页Chinese Journal of Applied Chemistry

基　　金：安阳市科委 2 0 0 0年资助项目 ( 2 0 0 0 64 )

摘　　要：N-Methylmorpholine was synthesized by alkylation of morpholine with chloromethane in sodium hydroxide solution. The influences of reaction temperature, reaction time and molar ratio of reactants on the yield of the reaction were examined. The optimum reaction conditions are as follows: reaction temperature 35 ℃, time 5 h, n(morpholine)∶n(monochloromethane)=1∶1.1, n(morpholine)∶n(sodium hydroxide)= 1∶1.2, yield of N-methylmorpholine 85%, purity 98%.N-Methylmorpholine was synthesized by alkylation of morpholine with chloromethane in sodium hydroxide solution. The influences of reaction temperature, reaction time and molar ratio of reactants on the yield of the reaction were examined. The optimum reaction conditions are as follows: reaction temperature 35 ℃, time 5 h, n(morpholine)∶n(monochloromethane)=1∶1.1, n(morpholine)∶n(sodium hydroxide)= 1∶1.2, yield of N-methylmorpholine 85%, purity 98%.

关 键 词：N-甲基吗啉 合成 一氯甲烷 

分 类 号：O621.3[理学—有机化学]