中国年轻男性精液质量与血清重金属含量的典型相关分析  

The Canonical Correlation Analysis on the Semen Quality and Serum Heavy Metal among Chinese Young Men

作　　者：梁翠玲[1] 武俊青[1] 高尔生[1] 杨秋英[1] 陶建国[1] 徐晓 蔡文娟 郭健 唐锋 朱江 付占海 杜银梅 

机构地区：[1]上海市计划生育科学研究所,计划生育药具国家重点实验室,200032 [2]河南省计划生育研究所,450003 [3]河北省计划生育研究所,200025 [4]山西省计划生育研究所,030006 [5]浙江省计划生育研究所,310012 [6]贵州省计划生育研究所,550004 [7]青岛计划生育研究所,266071 [8]山西省太原市卫生防疫站,030001

出　　处：《中国卫生统计》2003年第3期133-136,共4页Chinese Journal of Health Statistics

基　　金：上海市人口和计划生育委员会资助项目;项目号 :99JG0 1

摘　　要：目的　了解中国年轻男性的精液质量与血清重金属含量的相关关系。方法　研究对象为 1998年 12月至 1999年 12月在上海、河南、浙江、山西、青岛、河北、贵州七省市妇保所进行婚检的正常男性志愿者 5 2 9例。结果　调整地区因素后铅、镉与正常形态精子率存在负相关 ;但精液质量与血清重金属两组指标间的典型相关关系不明显。有两个省 (河南、贵州 )的典型相关分析结果有显著性 ,显示镉含量对正常形态精子率有不良影响 ;锰对精液质量的影响不明显 ;精子数量指标与血清重金属的关系不明显 ;河南的结果还表明铅影响精子的存活和形态。结论　总体而言 ,精液质量与血清重金属之间的典型相关关系不明显。但局部地区典型相关分析发现血清铅、镉可能对精子质量有不良影响。Objective To explore the correlation between the serum heavy metal and semen parameters among normal Chinese young Men. Methods The study population consisted of 562 male volunteers who accepted premarital physical examination in 7 MCH centers located in 7 provinces/city of China from Dec.1998 to Dec.1999.Results After adjustment for region, canonical correlation between semen quality and serum heavy metal were not significant. Canonical correlation analysis in the subjects of Henan and Guizhou showed the serum heavy metals didn't significantly influence the sperm quantity indexes, cadmium was harmful to normal sperm morphology. In Henan, furthermore, results showed lead and cadmium could negatively influence sperm viability and normal morphology (%). Conclusion In all study subjects, canonical correlation between semen quality and serum heavy metal were not significant; however, results in some region showed serum cadmium and lead might be harmful to sperm quality.

关 键 词：精液质量 重金属含量 铅 镉 典型相关分析 中国 

分 类 号：R181.3[医药卫生—流行病学]